Is MDMA a psychedelic? It’s tricky to say. Technically, it’s not - but, news coverage about the progress of the psychedelic movement often mentions MDMA. In many ways, MAPS (The Multidisciplinary Association for Psychedelic Studies - a pioneering psychedelic research nonprofit who we are in collaboration with - has made it a treatment that they are investing heavily in to make it the first drug they get to market for PTSD. It can enhance colors and sounds, but isn’t known to cause full-blown hallucinations. It also can be compared to more classic psychedelics - like LSD and mushrooms - because it can reduce fear and defensiveness, enhance communication and introspection, and increase empathy and compassion, enhancing the therapeutic process for people suffering from PTSD. This is why it’s most suited to be grouped with psychedelics, even though it isn’t one. Working with MDMA in the right setting, with the right therapist, can be life-changing.⠀
How to Stimulate Your Vagus Nerve for Better Mental Health
Adapted from - January 21, 2017 Jordan Fallis
“By developing an understanding of the workings of your vagus nerve, you may find it possible to work with your nervous system rather than feel trapped when it works against you.”
— Dr. Arielle Schwartz, Clinical Psychologist
Stimulating my vagus nerve has played a key role in the management of my mental health over the years.
What exactly is the vagus nerve?
The vagus nerve is the longest nerve in your body.
It connects your brain to many important organs throughout the body, including the gut (intestines, stomach), heart and lungs.
In fact, the word "vagus" means “wanderer” in Latin, which accurately represents how the nerve wanders all over the body and reaches various organs.
The vagus nerve is also a key part of your parasympathetic “rest and digest” nervous system. It influences your breathing, digestive function and heart rate, all of which can have a huge impact on your mental health.
But what you really need to pay special attention to is the "tone" of your vagus nerve. Vagal tone is an internal biological process that represents the activity of the vagus nerve.
Increasing your vagal tone activates the parasympathetic nervous system, and having higher vagal tone means that your body can relax faster after stress.
In 2010, researchers discovered a positive feedback loop between high vagal tone, positive emotions, and good physical health. In other words, the more you increase your vagal tone, the more your physical and mental health will improve, and vice versa (5).
“The vagal response reduces stress. It reduces our heart rate and blood pressure. It changes the function of certain parts of the brain, stimulates digestion, all those things that happen when we are relaxed.” — Dr. Mladen Golubic, MD, Medical Director of the Cleveland Clinic
What’s interesting is that studies have even shown that vagal tone is passed on from mother to child. Mothers who are depressed, anxious and angry during their pregnancy have lower vagal activity. And once they give birth to their child, the newborn also has low vagal activity and low dopamine and serotonin levels (1-3).
Your vagal tone can be measured by tracking certain biological processes such as your heart rate, your breathing rate, and your heart rate variability (HRV). When your heart rate variability (HRV) is high, your vagal tone is also high. They are correlated with each other (53-55).
If you’re vagal tone is low, don’t worry - you can take steps to increase it by stimulating your vagus nerve. This will allow you to more effectively respond to the emotional and physiological symptoms of your brain and mental illness.
For people with treatment-resistant depression, the FDA has even approved a surgically-implanted device that periodically stimulates the vagus nerve. (6-9).
But you don’t need to go down that route.
You can enjoy the benefits of vagus nerve stimulation naturally by following these steps.
1. Cold Exposure
Acute cold exposure has been shown to activate the vagus nerve and activate cholinergic neurons through vagus nerve pathways (10).
Researchers have also found that exposing yourself to cold on a regular basis can lower your sympathetic “fight or flight” response and increase parasympathetic activity through the vagus nerve (11).
I often take cold showers and go outside in cold temperatures with minimal clothing.
Try finishing your next shower with at least 30 seconds of cold water and see how you feel. Then work your way up to longer periods of time.
You can also ease yourself into it by simply sticking your face in ice-cold water.
2. Deep and Slow Breathing
Deep and slow breathing is another way to stimulate your vagus nerve.
It’s been shown to reduce anxiety and increase the parasympathetic system by activating the vagus nerve (51- 52).
Most people take about 10 to 14 breaths each minute. Taking about 6 breaths over the course of a minute is a great way to relieve stress. You should breathe in deeply from your diaphragm. When you do this, your stomach should expand outward. Your exhale should be long and slow. This is key to stimulating the vagus nerve and reaching a state of relaxation.
3. Singing, Humming, Chanting and Gargling
The vagus nerve is connected to your vocal cords and the muscles at the back of your throat. Singing, humming, chanting and gargling can activate these muscles and stimulate your vagus nerve. And this has been shown to increase heart-rate variability and vagal tone (12).
I often gargle water before swallowing it. This is discussed more in Dr. Datis Kharrazian’s book,
Why Isn’t My Brain Working?
It’s becoming increasingly clear to researchers that gut bacteria improve brain function by affecting the vagus nerve (27).
In one study, animals were given the probiotic Lactobacillus Rhamnosus, and researchers found positive changes to the GABA receptors in their brain, a reduction in stress hormones, and less depression and anxiety-like behaviour.
The researchers also concluded that these beneficial changes between the gut and the brain were facilitated by the vagus nerve. When the vagus nerve was removed in other mice, the addition of Lactobacillus Rhamnosus to their digestive systems failed to reduce anxiety, stress, and improve mood (25).
Another study found that the probiotic Bifidobacterium Longum normalized anxiety-like behavior in mice by acting through the vagus nerve (26).
Meditation is my favourite relaxation technique and it can stimulate the vagus nerve and increase vagal tone.
Research shows that meditation increases vagal tone and positive emotions, and promotes feelings of goodwill towards yourself (22, 23). Another study found that meditation reduces sympathetic “fight or flight” activity and increases vagal modulation (21).
6. Omega-3 Fatty Acids
Omega-3 fatty acids are essential fats that your body cannot produce itself. They are found primarily in fish and are necessary for the normal electrical functioning of your brain and nervous system.
They often appear in most of my posts because they are so critical for brain and mental health and affect so many aspects of wellness. They’ve been shown to help people overcome addiction, repair a “leaky brain”, and even reverse cognitive decline.
But researchers have also discovered that omega-3 fatty acids increase vagal tone and vagal activity (35-37, 40). Studies shown that they reduce heart rate and increase heart rate variability, which means they likely stimulate the vagus nerve (34, 38, 39).
And high fish consumption is also associated with “enhanced vagal activity and parasympathetic predominance” (35).
I’ve already discussed how exercise increases your brain’s growth hormone, supports your brain’s mitochondria, and helps reverse cognitive decline.
But it’s also been shown to stimulate the vagus nerve, which may explain its beneficial brain and mental health effects (28).
Many brain health experts recommend exercise as their number one piece of advice for optimal brain health. Choose a sport or exercise routine that you enjoy, so that you will stick with it consistently.
Research shows that massages can stimulate the vagus nerve, and increase vagal activity and vagal tone (31- 32).
The vagus nerve can also be stimulated by massaging several specific areas of the body.Foot massages (reflexology) have been shown to increase vagal modulation and heart rate variability, and decrease the “fight or flight” sympathetic response (29). Massaging the carotid sinus, an area located near the right side of your throat, can also stimulate the vagus nerve to reduce seizures (30).
9. Socializing and Laughing
I’ve already discussed how socializing and laughing can reduce your body’s main stress hormone. And now I’ve now that they are likely doing this by stimulating the vagus nerve.
Researchers have discovered that reflecting on positive social connections improves vagal tone and increases positive emotions (47, 48).
Laughter has been shown to increase heart-rate variability and improve mood (49). And vagus nerve stimulation often leads to laughter as a side effect, suggesting that they are connected and influence one another (50).
So my advice is to hang out and laugh with your friends as much as possible. Although I should probably be taking my own advice here, as I’m an introvert and often avoid socializing too much.
You don’t have to be controlled by your body and mind. You have the power to tell them what to do.
By stimulating the vagus nerve, you can send a message to your body that it’s time to relax and de-stress, which leads to long-term improvements in mood, wellbeing and resilience.
Increasing my vagal tone has allowed me to overcome anxiety and depression, and better manage them when they arise.
Overall, I hope you implement some of the above steps into your daily life, and they allow you to live more optimally.
WELCOME TO LUMINOUS HEALING CENTER
Our founding organization, The Lotus Collaborative has been serving the Bay Area and California online communities for the past 10 years! Lotus offered comprehensive support for trauma, mood disorders and eating disorders. Lotus founded Luminous to offer MDMA-Assisted Psychotherapy to our communities.
Our big news that we are so pleased to announce is that in the new year, Luminous Healing Center will be offering MDMA-assisted psychotherapy for patients diagnosed with post traumatic stress disorder (PTSD).
We are excited to be one of the few clinics in the United States with the ability to offer this treatment through an Expanded Access Program under the guidance of the Food and Drug Administration (FDA), the Drug Enforcement Administration (DEA) and in collaboration with Multidisciplinary Association for Psychedelic Studies (MAPS) Public Benefit Corporation (MAPS PBC).
Information regarding enrollment will be coming in the next few months, and you can stay up to date with our newsletter sign-up form below.
The FDA provided ‘Break Through Therapy Designation’ for MDMA-assisted psychotherapy in 2017. We hope this marks the beginning of a major shift in mental healthcare. Our team is looking forward to being one of the few clinics to offer MDMA-assisted psychotherapy as part of an Expanded Access Program in the new year.
Our highest goal at Lotus and Luminous is to keep our staff and patients safe during a pandemic. We also are committed to providing life saving treatments to our communities and will work hard to offer the most innovative, cutting edge, effective treatments possible. As we continue to get green-lit to begin offering this service, we will send updates via newsletter and here on our website.
Stay tuned for more updates from us in the coming months! Please click on our newsletter link to stay informed.